Temperature – Higher temperature increases the random motion of molecules and thus higher is the rate of diffusionConcentration – Higher the concentration gradient between the regions undergoing diffusion, more is the rate of diffusionDistance – The rate of diffusion is faster in smaller distancesSize of the molecules – Smaller the size of the molecule, faster is the rate of diffusion and vice versa.
- Mediated by Channel Proteins – Span the membrane and create a channel through them to transport molecules or ions in and out of the cell
- Mediated by Carrier Proteins – Carry the molecules or ions across the membrane by changing their shape after binding
